Inhibition of phosphoglucomutase by trace metals
نویسندگان
چکیده
منابع مشابه
The inhibition of phosphoglucomutase by beryllium.
1. The inhibition of phosphoglucomutase by beryllium has been examined. 2. Inhibition by beryllium does not occur unless a complex-forming agent such as cysteine or imidazole is present. It is therefore similar to activation by magnesium. 3. The inhibition is progressive and the rate follows first-order kinetics, which may be defined by a bimolecular rate constant. 4. In the presence of magnesi...
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The activation of phosphoglucomutase prior to the enzymic assay is interpreted in terms of the direct removal of inhibiting metals or their replacement by Mg2+ which occurs readily only in the absence or in the presence of very low concentrations of substrate. Inhibition of the enzyme by high concentrations of Mg2f is caused by the formation of inactive magnesium complexes of glucose l-phosphat...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1961
ISSN: 0306-3283
DOI: 10.1042/bj0790591